The first International Workshop on Sensing, Processing and Learning for Intelligent Machines (SPLINE 2016) provides an opportunity for researchers and developers from both academia and industry to present their work, bring state-of-the-art forward and facilitate an active and constructive exchange of ideas on current areas of interest. SPLINE 2016 will be held in Aalborg, Denmark between July 6 and 8, 2016. The proceedings of the workshop will be published by.